A versatile mouse model to advance human microglia transplantation research in neurodegenerative diseases
Summary
The hCSF1Bdes mouse is available for both non-profit and for-profit organisations, facilitating the use of the xenotransplantation paradigm for human microglia to study complex human disease. © 2025. The Author(s).
| Authors | Serneels L, Sierksma A, Pasciuto E, Geric I, Nair A, Martinez-Muriana A, Snellinx A, De Strooper B |
|---|---|
| Journal | Molecular neurodegeneration |
| Publication Date | 2025 Mar 11;20(1):29 |
| PubMed | 40069774 |
| PubMed Central | PMC11895352 |
| DOI | 10.1186/s13024-025-00823-2 |