CHOPi002-A

Cell Line

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External Databases

General Information

• Maguire JA et al. Generation of Spinocerebellar Ataxia Type 2 induced pluripotent stem cell lines, CHOPi002-A and CHOPi003-A, from patients with abnormal CAG repeats in the coding region of the ATXN2 gene. Stem cell research. 2019 Jan;34:101361.
• Egorova PA et al. Molecular Mechanisms and Therapeutics for Spinocerebellar Ataxia Type 2. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2019 Oct;16(4):1050-1073.
• Naphade S et al. Modeling Polyglutamine Expansion Diseases with Induced Pluripotent Stem Cells. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2019 Oct;16(4):979-998.
• Slanzi A et al. In vitro Models of Neurodegenerative Diseases. Frontiers in cell and developmental biology. 2020;8:328.
• Egorova P. A. et al. New Approaches in Studies of the Molecular Pathogenesis of Type 2 Spinocerebellar Ataxia. Neuroscience and Behavioral Physiology. 2020-09-00.
• Leavens KF et al. Generation of a double insulin and somatostatin reporter line, SCSe001-A-3, for the advancement of stem cell-derived pancreatic islets. Stem cell research. 2020 Dec 8;50:102112.
• Appelt PA et al. Effect of stem cell treatment on functional recovery of spinocerebellar ataxia: systematic review and meta-analysis. Cerebellum & ataxias. 2021 Feb 25;8(1):8.
• Correia JS et al. Cell-based therapeutic strategies for treatment of spinocerebellar ataxias: an update. Neural regeneration research. 2023 Jun;18(6):1203-1212.
• Takasaki K et al. Generation of 2 isogenic clones from a patient with Trisomy 21 and a GATA1 mutation. Stem cell research. 2023 Jun;69:103098.
• Hashmi SK et al. Generation of CHOPe003-A ESC line to study an ACTG2 variant affecting smooth muscle development and function. Stem cell research. 2023 Sep;71:103186.
• Hashmi SK et al. Generation of CHOPi012-A iPSC line from a patient with visceral myopathy-related chronic intestinal pseudo-obstruction. Stem cell research. 2023 Sep;71:103176.
• Takasaki K et al. Generation of CHOPi-008-B, a euploid iPSC line from a patient with Trisomy 21 and a GATA1 mutation. Stem cell research. 2023 Oct;72:103198.
• Pham Vi et al. A novel iPSC model reveals selective vulnerability of neurons in multiple sulfatase deficiency. Molecular Genetics and Metabolism. 2023-12-00.
• Raghunathan N et al. A comprehensive review of iPS cell line-based disease modelling of the polyglutamine spinocerebellar ataxias 2 and 3: a focus on the research outcomes. Ann Med Surg (Lond). 2024-03-19.
• Leavens Karla F. et al. Generation of a fluorescent mNeonGreen insulin reporter line in the H1 (WA01) hESC background. Stem Cell Research. 2024-12-00.

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