HVRDe008-A-1

Registration Summary:

A P E C

The cell line is not submitted yet.

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General

Cell Line
hPSCreg name	HVRDe008-A-1
Cite as:	HVRDe008-A-1 (RRID:CVCL_A8ZA)
Cell line type	Human embryonic stem cell (hESC)
Similar lines	No similar lines found.
Last update	3rd May 2021
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Provider
Generator	Melton Lab (MLB) Contact: Harvard University (HVRD)
External Databases
BioSamples	SAMEA8633544
Cellosaurus	CVCL_A8ZA
Wikidata	Q108820515
General Information
Publications	Gerace D et al. Generation of a heterozygous GAPDH-Luciferase human ESC line (HVRDe008-A-1) for in vivo monitoring of stem cells and their differentiated progeny. Stem cell research. 2021 May;53:102371. Sintov E et al. A human ESC line for efficient CRISPR editing of pluripotent stem cells. Stem cell research. 2021 Dec;57:102591. Bartolomé A. Stem Cell-Derived β Cells: A Versatile Research Platform to Interrogate the Genetic Basis of β Cell Dysfunction. International journal of molecular sciences. 2022 Jan 2;23(1). Sintov E et al. Whole-genome CRISPR screening identifies genetic manipulations to reduce immune rejection of stem cell-derived islets. Stem cell reports. 2022 Sep 13;17(9):1976-1990. Reé D et al. Partial Disturbance of Microprocessor Function in Human Stem Cells Carrying a Heterozygous Mutation in the DGCR8 Gene. Genes. 2022 Oct 23;13(11). Gerace D et al. Engineering human stem cell-derived islets to evade immune rejection and promote localized immune tolerance. Cell reports. Medicine. 2023 Jan 17;4(1):100879. Dewal Revati S. et al. Transplantation of committed pre-adipocytes from brown adipose tissue improves whole-body glucose homeostasis. iScience. 2024-02-00.
* Is the cell line readily obtainable for third parties?	Yes Research use: allowed Clinical use: not allowed Commercial use: not allowed
Subclone of	HVRDe008-A