UOWi005-A

Registration Summary:

A P E C

CCNF, CCNF2

The cell line is not submitted yet.

(only basic data is shown)

General

Cell Line
hPSCreg name	UOWi005-A
Cite as:	UOWi005-A (RRID:CVCL_VF31)
Alternative name(s)	CCNF, CCNF2
Cell line type	Human induced pluripotent stem cell (hiPSC)
Similar lines	No similar lines found.
Last update	30th January 2018
User feedback	Written by on No feedback available yet. Login to share your feedback, experiences or results with the research community.
Provider
Generator	University of Wollongong (UOW)
External Databases
Cellosaurus	CVCL_VF31
Wikidata	Q54991430
General Information
Publications	Bax M et al. Generation and characterization of a human induced pluripotent stem cell line UOWi005-A from dermal fibroblasts derived from a CCNF(S621G) familial amyotrophic lateral sclerosis patient using mRNA reprogramming. Stem cell research. 2019 Oct;40:101530. Cheng F et al. Unbiased Label-Free Quantitative Proteomics of Cells Expressing Amyotrophic Lateral Sclerosis (ALS) Mutations in CCNF Reveals Activation of the Apoptosis Pathway: A Workflow to Screen Pathogenic Gene Mutations. Frontiers in molecular neuroscience. 2021;14:627740. Farrawell Natalie E et al. ALS-linked CCNF variant disrupts motor neuron ubiquitin homeostasis. Human Molecular Genetics. 2023-07-04. Davidson Jennilee M. et al. The E3 Ubiquitin Ligase SCF Cyclin F Promotes Sequestosome-1/p62 Insolubility and Foci Formation and is Dysregulated in ALS and FTD Pathogenesis. Molecular Neurobiology. 2023-09-00. Ragagnin Audrey M. G. et al. ALS/FTD-associated mutation in cyclin F inhibits ER-Golgi trafficking, inducing ER stress, ERAD and Golgi fragmentation. Scientific Reports. 2023-11-22. Bax Monique et al. Generation of induced pluripotent stem cell lines from a sister pair who suffered post-partum or recurrent Spontaneous Coronary Artery Dissections. Stem Cell Research. 2023-12-00.

hIPSC Derivation

General
Source cell line name	MB2-1