UTSWi002-A-2

FA2-N

General

Cell Line

hPSCreg name UTSWi002-A-2
Cite as:
UTSWi002-A-2
Alternative name(s)
FA2-N
Cell line type Human induced pluripotent stem cell (hiPSC)
Similar lines
UTSWi002-A
(FA2)
Donor diseases:
Friedreich Ataxia
UTSWi002-A-1
(FA2ic)
Donor diseases:
Friedreich Ataxia
UTSWi002-A-3
(FA2ic-N)
Donor diseases:
Friedreich Ataxia
UTSWi001-A-1
(FA1ic)
Donor diseases:
Friedreich Ataxia
UTSWi003-A-1
(FA3ic)
Donor's gene variants:
fxn
Donor diseases:
Friedreich Ataxia
IGIBi012-A
(FA-hiPSC_001)
Donor diseases:
Friedreich Ataxia
IGIBi013-A
(FA_hiPSC_002)
Donor diseases:
Friedreich Ataxia
IGIBi016-A
(FA-hiPSC_005)
Donor diseases:
Friedreich Ataxia
UTSWi001-A
(FA1)
Donor diseases:
Friedreich Ataxia
USFi001-A
(1CN1.5)
Donor diseases:
Friedreich Ataxia
UTSWi001-A-3
(FA1ic-N)
Donor diseases:
Friedreich Ataxia
UTSWi003-A
(FA3)
Donor's gene variants:
fxn
Donor diseases:
Friedreich Ataxia
UTSWi001-A-2
(FA1-N)
Donor diseases:
Friedreich Ataxia
UTSWi003-A-2
(FA3-N)
Donor's gene variants:
fxn
Donor diseases:
Friedreich Ataxia
UTSWi003-A-3
(FA3ic-N)
Donor's gene variants:
fxn
Donor diseases:
Friedreich Ataxia
Last update 4th June 2024
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Provider

Generator University of Wollongong (UOW)

External Databases

BioSamples SAMEA115432925

General Information

* Is the cell line readily obtainable for third parties?
Yes
Research use: allowed
Clinical use: not allowed
Commercial use: not allowed
Subclone of

Donor Information

General Donor Information

Sex male

Phenotype and Disease related information (Donor)

Diseases A disease was diagnosed.
The donor is a carrier of a disease-associated mutation and affected.
Synonyms
  • Friedreich's Ataxia
  • Friedreich Ataxia
  • Friedreich ataxia
Is the medical history available upon request? limited
Is clinical information available? limited

Other Genotyping (Donor)

Is there genome-wide genotyping or functional data available?
No

External Databases (Donor)

BioSamples SAMEA115428748

Ethics

Also have a look at the ethics information for the parental line UTSWi002-A .
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?

hIPSC Derivation

General

The source cell information can be found in the parental cell line UTSWi002-A.

Reprogramming method

Vector type Non-integrating
Vector Sendai virus

Vector free reprogramming

Other

Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

Culture Conditions

Surface coating Vitronectin
Feeder cells
No
Passage method Enzyme-free cell dissociation
EDTA
Medium Essential 8™

Characterisation

No characterisation data could be found for this subclone. Please open parental cell line UTSWi002-A .

Genotyping

Karyotyping (Cell Line)

Other Genotyping (Cell Line)

Genetic Modification

Genetic modifications not related to a disease
Transgene expression
13q32.3
This line expresses Neurogenin 2 under a doxycycline inducible promoter. The line also contains a floxed Blasticidin resistance/nuclear mApple selection cassette.
CRISPR-associated (CRISPR/Cas) System