Cell Line

hPSCreg Name
Alternative name(s)
Cell line type Human induced pluripotent stem cell (hiPSC)
Last update 22nd May 2019
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Generator Wellcome Trust Sanger Institute (WTSI)

External Databases

HipSci HPSI0616i-kulz_3
BioSamples SAMEA17509168
ECACC 77650581
Cellosaurus CVCL_IZ27
CLO CLO_0102239
Wikidata Q54891208

General Information

* Is the cell line readily obtainable for third parties?
Research use: allowed
Clinical use: not allowed
Commercial use: not allowed

Donor Information

General Donor Information

Sex female
Age of donor (at collection) 60-64
Ethnicity Any Other Asian Background - Seychellwa/Srilankan

Phenotype and Disease related information (Donor)

Diseases A disease was diagnosed.
hematologic disease
  • Hematologic Diseases
  • blood disorder
  • hematopoietic system disease
  • hematologic disease
  • hematological disorder
  • disorder of hematopoietic system
  • hematopoietic system disease or disorder
  • hematopoietic disease
  • hematological system disease
  • disease of hematopoietic system
  • blood disease
  • haematological system disorder
  • hematologic and lymphocytic disorder
  • rare hematologic disease
  • disease of the blood and blood-forming organs
  • hematologic disorder
  • hematological system disorder
  • blood dyscrasia
  • haematological system disease
  • hematological disease
  • disease or disorder of hematopoietic system
show more synonyms

Donor Relations

Other cell lines of this donor

External Databases (Donor)

BioSamples SAMEA4459410


Has informed consent been obtained from the donor of the embryo/tissue from which the pluripotent stem cells have been derived? Yes
Was the consent voluntarily given? Yes
Has the donor been informed that participation will not directly influence their personal treatment? Yes
Can you provide us with a copy of the Donor Information Sheet provided to the donor? Yes
Do you (Depositor/Provider) hold the original Donor Consent Form? No
If you do not hold the Donor Consent Form, do you know who does? No
Alternatives to consent
Is there other documentation provided to the donor for consenting purposes? Yes
Please indicate whether the data associated with the donated material has been pseudonymised or anonymised. anonymised
Does consent explicitly allow the derivation of pluripotent stem cells? Yes
Does consent expressly prevent the derivation of pluripotent stem cells? No
Does consent prevent CELLS DERIVED FROM THE DONATED BIOSAMPLE from being made available to researchers anywhere in the world? No
How may genetic information associated with the cell line be accessed?
Will the donor expect to receive financial benefit, beyond reasonable expenses, in return for donating the biosample? No
Has a favourable opinion been obtained from a research ethics committee, or other ethics review panel, in relation to the Research Protocol including the consent provisions? Yes
Name of accrediting authority involved? East of England- Cambridge Central Research Ethics Committee.
Has a favourable opinion been obtained from a research ethics committee, or other ethics review panel, in relation to the PROPOSED PROJECT, involving use of donated embryo/tissue or derived cells? No

hIPSC Derivation


Source cell type
A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped.
Source cell origin
zone of skin
Any portion of the organ that covers that body and consists of a layer of epidermis and a layer of dermis.
Age of donor (at collection) 60-64
Collected in 2016
Source cell line vendor Cambridge BioResource

Reprogramming method

Vector type Non-integrating
Vector Sendai virus
Notes on reprogramming vector detection CytoTune 2

Vector free reprogramming


Derived under xeno-free conditions
Derived under GMP?
Available as clinical grade?

Culture Conditions

Surface coating Vitronectin
Feeder cells
Passage method Enzyme-free cell dissociation
CO2 Concentration 5 %
Medium TeSR™ E8™


Analysis of Undifferentiated Cells
Pluripotency Score Novelty Score
44.602 1.37

Certificate of Analysis

Is there a certificate of analysis available?


Karyotyping (Cell Line)

Has the cell line karyotype been analysed?

Other Genotyping (Cell Line)

Is there genome-wide genotyping or functional data available?
Number of regions different from primary tissue: 0; Length of differences from primary tissue: 0
Exome sequencing
mpileup variant calls
Exome sequencing
BWA alignment
Exome sequencing
Raw sequencing reads
Abundances of transcripts
Splice-aware STAR alignment