IMBAi017-A-1

Pat.2 ARID1B+/+ clone 2c (XX)

General

Cell Line

hPSCreg name IMBAi017-A-1
Cite as:
IMBAi017-A-1
Alternative name(s)
Pat.2 ARID1B+/+ clone 2c (XX)
Cell line type Human induced pluripotent stem cell (hiPSC)
Similar lines No similar lines found.
Last update 28th August 2024
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Provider

Generator Institute of Molecular Biotechnology (IMBA)
Derivation country Austria

External Databases

BioSamples SAMEA115960551

General Information

Publications
* Is the cell line readily obtainable for third parties?
Yes
Research use: allowed
Clinical use: not allowed
Commercial use: allowed
Subclone of

Donor Information

General Donor Information

Sex female

Phenotype and Disease related information (Donor)

Diseases A disease was diagnosed.
The donor is a carrier of a disease-associated mutation and affected.
Synonyms
  • Coffin-Siris Syndrome

External Databases (Donor)

BioSamples SAMEA115296939

Ethics

Also have a look at the ethics information for the parental line IMBAi017-A .
Is there an MTA available for the cell line? Yes
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?
Are you aware of any constraints on the use or distribution of the cell line from the owner or any parties identified in the query above? No

hIPSC Derivation

General

The source cell information can be found in the parental cell line IMBAi017-A.

Reprogramming method

Vector type Non-integrating
Vector Sendai virus
Is reprogramming vector detectable?
No
Methods used
RT-PCR

Vector free reprogramming

Other

Derived under xeno-free conditions
No
Derived under GMP?
No
Available as clinical grade?
No

Culture Conditions

Surface coating Matrigel/Geltrex
Medium mTeSR™ Plus

Characterisation

No characterisation data could be found for this subclone. Please open parental cell line IMBAi017-A .

Genotyping

Karyotyping (Cell Line)

Has the cell line karyotype been analysed?
Yes
X X

Other Genotyping (Cell Line)

Genetic Modification

Disease/phenotype related modifications
Repair of ARID1B mutation
Synonyms
  • Coffin-Siris Syndrome
Genetic modifications
arid1b (target)
Gene knock-in
Chromosome 6: 157,099,063-157,531,913
CRISPR-associated (CRISPR/Cas) System