IMBAi001-A-1

HD.1 ARID1B+/- clone 3b (XX)

General

Cell Line

hPSCreg name IMBAi001-A-1
Cite as:
IMBAi001-A-1 (RRID:CVCL_E4GR)
Alternative name(s)
HD.1 ARID1B+/- clone 3b (XX)
Cell line type Human induced pluripotent stem cell (hiPSC)
Similar lines No similar lines found.
Last update 28th August 2024
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Provider

Generator Institute of Molecular Biotechnology (IMBA)
Derivation country Austria

External Databases

BioSamples SAMEA115958748
Cellosaurus CVCL_E4GR

General Information

Publications
* Is the cell line readily obtainable for third parties?
Yes
Research use: allowed
Clinical use: not allowed
Commercial use: allowed
Subclone of

Donor Information

General Donor Information

Sex female
Ethnicity Caucasian

Phenotype and Disease related information (Donor)

Diseases No disease was diagnosed.
Family history no
Is the medical history available upon request? no
Is clinical information available? no

Other Genotyping (Donor)

Is there genome-wide genotyping or functional data available?
Yes

Donor Relations

Other cell lines of this donor

External Databases (Donor)

BioSamples SAMEA110247345

Ethics

Also have a look at the ethics information for the parental line IMBAi001-A .
Is there an MTA available for the cell line? Yes
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?
Are you aware of any constraints on the use or distribution of the cell line from the owner or any parties identified in the query above? No

hIPSC Derivation

General

The source cell information can be found in the parental cell line IMBAi001-A.

Reprogramming method

Vector type Non-integrating
Vector Sendai virus
Is reprogramming vector detectable?
No
Methods used
RT-PCR

Vector free reprogramming

Other

Derived under xeno-free conditions
No
Derived under GMP?
No
Available as clinical grade?
No

Culture Conditions

Medium Other medium:
Base medium:
Main protein source:
Serum concentration: %

Characterisation

Analysis of Undifferentiated Cells
Morphology pictures
Differentiation Potency

Microbiology / Virus Screening

HIV 1 Negative
HIV 2 Negative
Hepatitis B Negative
Hepatitis C Negative
Mycoplasma Negative

Genotyping

Karyotyping (Cell Line)

Has the cell line karyotype been analysed?
Yes
X X
Karyotyping method: Molecular karyotyping by SNP array
http://

Other Genotyping (Cell Line)

Genetic Modification

Disease/phenotype related modifications
Synonyms
  • Coffin-Siris Syndrome
Genetic modifications
arid1b (target)
Gene knock-in
Chromosome 6: 157,099,063-157,531,913
CRISPR-associated (CRISPR/Cas) System