WETU LRP2 KO

General#

Cell Line

hPSCreg Name WTSIi227-A-1
Alternative name(s)
WETU LRP2 KO
Cell line type Human induced pluripotent stem cell (hiPSC)
Last update 26th April 2018
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Provider

Generator Berlin Institute of Health (BIH)
Distributors

External Databases

BioSamples SAMEA4861651
Cellosaurus CVCL_VN07

General Information

Notes LRP2 KO cell line
Is the cell line available in principle? Available with restrictions: Available for non-commercial research
Subclone of

Donor Information#

General Donor Information

Sex female
Ethnicity White - White British

Phenotype and Disease related information (Donor)

Diseases No disease was diagnosed.

External Databases (Donor)

BioSamples SAMEA2398744

Ethics#

We are currently revising this section.

hIPSC Derivation#

General

The source cell information can be found in the parental cell line WTSIi227-A.

Reprogramming method

Vector type Non-integrating
Vector Sendai virus

Vector free reprogramming

Other

Derived under xeno-free conditions
Unkown
Derived under GMP?
Unkown
Available as clinical grade?
Unkown

Culture Conditions#

Surface coating Matrigel/Geltrex
Feeder cells
No
Medium Essential 8™

Characterisation#

Analysis of Undifferentiated Cells
Marker Expressed Immunostaining RT-PCR FACS Enzymatic Assay Expression Profiles
NANOG
Yes
SSEA-4
Yes
SOX2
Yes

Genotyping#

Karyotyping (Cell Line)

Other Genotyping (Cell Line)

Genetic Modification#

Disease/phenotype related modifications
Donnai-Barrow syndrome
Synonyms
  • Holmes-Schepens syndrome
  • Facio-oculo-acoustico-renal syndrome
  • Syndrome of ocular and facial anomalies, telecanthus and deafness
  • Diaphragmatic hernia-hypertelorism-myopia-deafness syndrome
  • FOAR syndrome
  • DBS/FOAR syndrome
  • Diaphragmatic hernia-exomphalos-hypertelorism syndrome
show more synonyms
Genetic modifications
LRP2 (target)
Gene knock-out
CRISPR-associated (CRISPR/Cas) System