INSRMe004-A

STR-I-171-GLA

General

Cell Line

hPSCreg name INSRMe004-A
Cite as:
INSRMe004-A (RRID:CVCL_C083)
Alternative name(s)
STR-I-171-GLA
Cell line type Human embryonic stem cell (hESC)
Similar lines
CMCi006-A-1
(CMC-Fb001(A4GALT-KO))
Donor diseases:
Fabry Disease
CMCi010-A
(CMC-Fb-002)
Donor diseases:
Fabry Disease
CMCi007-A
(CMC-Fb-004)
Donor diseases:
Fabry Disease
UKWNLi006-B
(GLA-D170N-iPSC-2, GLA-508G>A-2, FD1089/21)
Donor diseases:
Fabry Disease
UKWNLi007-B
(GLA-515-G>A-2, FD1210/2, GLA-C172Y-iPSC-2)
Donor diseases:
Fabry Disease
CMCi006-A
(CMC-Fb-001)
Donor diseases:
Fabry Disease
CTGUi001-A
(FD01, F01)
Donor diseases:
Fabry Disease
INSAi002-A
Donor diseases:
Fabry Disease
UKWNLi006-A
(GLA-D170N-iPSC-1, FD1089/20, GLA-508G>A-1)
Donor diseases:
Fabry Disease
UKWNLi007-A
(GLA-515G>A-1, GLA-C172Y-iPSC-1, FD1210/1)
Donor diseases:
Fabry Disease
INSRMi005-A
(PC119_c7)
Last update 3rd September 2022
User feedback
No feedback available yet.

Login to share your feedback, experiences or results with the research community.

Provider

Generator INSERM (INSRM)
Derivation country France

External Databases

Cellosaurus CVCL_C083
Wikidata Q54970609

General Information

Publications
* Is the cell line readily obtainable for third parties?
Yes

Donor Information

General Donor Information

Sex female

Phenotype and Disease related information (Donor)

Diseases A disease was diagnosed.
The donor is affected.
Synonyms
  • Alpha-galactosidase A deficiency
  • Angiokeratoma Corporis Diffusum
  • Fabry's disease
  • alpha galactosidase deficiency
  • deficiency of melibiase
  • Fabry Disease, Cardiac Variant
show more synonyms
Disease associated phenotypes
  • Turner Syndrom

Donor Relations

All cell lines of this donor's relatives
Has mother:

Ethics

Alternatives to consent are available? Yes
Alternatives to consent
Alternative consent approval number
How may genetic information associated with the cell line be accessed?

hESC Derivation

Embryo stage Blastula with ICM and Trophoblast
PGD Embryo?
Yes
ZP removal technique Enzymatic

Culture Conditions

Surface coating Gelatin
Passage method Mechanically
CO2 Concentration 5 %
Medium Other medium:
Base medium: Knockout-DMEM
Main protein source: Knock-out serum replacement
Serum concentration: 20 %
Supplements
L-Glutamine
bFGF

Characterisation

Differentiation Potency
Endoderm
Ont Id: UBERON_0000925
In vitro spontaneous differentiation
Mesoderm
Ont Id: UBERON_0000926
In vitro spontaneous differentiation
Ectoderm
Ont Id: UBERON_0000924
In vitro spontaneous differentiation

Microbiology / Virus Screening

HIV 1 Negative
HIV 2 Negative
Hepatitis B Negative
Hepatitis C Negative

Genotyping

Karyotyping (Cell Line)

Has the cell line karyotype been analysed?
Yes
45, XO

Other Genotyping (Cell Line)