MRIi016-A-2

General

Cell Line

hPSCreg name MRIi016-A-2
Cite as:
MRIi016-A-2 (RRID:CVCL_D0EB)
Cell line type Human induced pluripotent stem cell (hiPSC)
Similar lines No similar lines found.
Last update 2nd February 2023
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Provider

Generator Institute of Human Genetics Heidelberg (UKHG)

External Databases

BioSamples SAMEA112465910
Cellosaurus CVCL_D0EB
Wikidata Q123033124

General Information

Publications
* Is the cell line readily obtainable for third parties?
Yes
Research use: allowed
Clinical use: not allowed
Commercial use: not allowed
Subclone of

Donor Information

General Donor Information

Sex male

Phenotype and Disease related information (Donor)

Diseases A disease was diagnosed.
The donor is a carrier of a disease-associated mutation and affected.
Synonyms
  • AFib
  • AF
  • Atrial fibrillation
  • Atrial Fibrillation
show more synonyms

Karyotyping (Donor)

Has the donor karyotype been analysed?
Yes
46 XY

Other Genotyping (Donor)

Is there genome-wide genotyping or functional data available?
No

External Databases (Donor)

BioSamples SAMEA9438087

Ethics

Also have a look at the ethics information for the parental line MRIi016-A .
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?

hIPSC Derivation

General

The source cell information can be found in the parental cell line MRIi016-A.

Reprogramming method

Vector type Non-integrating
Vector Sendai virus

Vector free reprogramming

Other

Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

Culture Conditions

Surface coating Matrigel/Geltrex
Feeder cells
No
Medium Other medium:
Base medium: StemFit
Main protein source:
Serum concentration: %

Characterisation

No characterisation data could be found for this subclone. Please open parental cell line MRIi016-A .

Genotyping

Karyotyping (Cell Line)

Has the cell line karyotype been analysed?
Yes
46 XY

Other Genotyping (Cell Line)

Genetic Modification

Disease/phenotype related modifications
Synonyms
  • A-fib
Genetic modifications
SHOX2 (target)
Isogenic modification
Repaired
SHOX2 (target)
Gene knock-out
CRISPR-associated (CRISPR/Cas) System