SCZ 3.5

General

Cell Line

hPSCreg name VUi011-A
Cite as:
VUi011-A (RRID:CVCL_ZB12)
Alternative name(s)
SCZ 3.5
Cell line type Human induced pluripotent stem cell (hiPSC)
Similar lines
VUi005-A
(787.3)
Donor diseases:
Schizophrenia
VUi006-A
(SCZ 21.5)
Donor diseases:
Schizophrenia
VUi008-A
(SCZ 6.2)
Donor diseases:
Schizophrenia
VUi009-A
(SCZ 10.1)
Donor diseases:
Schizophrenia
VUi010-A
(SCZ 1.1)
Donor diseases:
Schizophrenia
VUi012-A
(SCZ 7.2)
Donor diseases:
Schizophrenia
VUi013-A
(804.3)
Donor diseases:
Schizophrenia
VUi017-A
(SCZ4.3)
Donor diseases:
Schizophrenia
VUi024-A
(SCZ 9.4)
Donor diseases:
Schizophrenia
MLUi001-M
Donor diseases:
Schizophrenia
MLUi002-G
Donor diseases:
Schizophrenia
NMIi002-A
Donor diseases:
Schizophrenia
NMIi005-A
Donor diseases:
Schizophrenia
NMIi002-B
Donor diseases:
Schizophrenia
MHRCCGi001-A
(P1SH)
Donor diseases:
Schizophrenia
SZGJMSi001-A
(ZLP-2)
Donor diseases:
Schizophrenia
NMIi004-A
Donor diseases:
Schizophrenia
NMIi006-A
Donor diseases:
Schizophrenia
NMIi006-B
Donor diseases:
Schizophrenia
WCHi006-A
Donor diseases:
Schizophrenia
WCHi003-A
Donor diseases:
Schizophrenia
UJSi001-A
Donor diseases:
Schizophrenia
LUMCi002-A
(113-6, LUMC0113iATAX06)
Donor diseases:
Spinocerebellar Ataxia Type 1
LUMCi002-B
(113-7, LUMC0113iATAX07)
Donor diseases:
Spinocerebellar Ataxia Type 1
LUMCi002-C
(113-8, LUMC0113iATAX08)
Donor diseases:
Spinocerebellar Ataxia Type 1
DHMi004-A
(HOS_1460)
Donor diseases:
Holt-Oram Syndrome
HDZi003-A
(hiPSC NP0038)
Donor's gene variants:
TMEM43
Donor diseases:
arrhythmogenic right ventricular dysplasia 5
FRIMOi004-A
(STGD2_ FiPS4F1.7)
Donor diseases:
Stargardt Disease
HIHDNDi001-A
(A30P-3, SNCA3, Tue_020_A)
Donor's gene variants:
SNCA, SNCA, SNCA
Donor diseases:
autosomal dominant Parkinson disease 1
HIHDNDi001-B
(A30P-4, SNCA4, Tue_020_B)
Donor's gene variants:
SNCA, SNCA, SNCA
Donor diseases:
autosomal dominant Parkinson disease 1
ZZUi026-A
(ZZU-iPS-SCA3-003)
Donor diseases:
Spinocerebellar Ataxia Type 3
ZZUi030-A
(ZZU-iPS-SPG7-001)
Donor diseases:
Spastic paraplegia type 7
UNIZARi001-A
(FiPSTK2-2)
Donor's gene variants:
TK2, TK2
Donor diseases:
Mitochondrial DNA depletion syndrome, myopathic form
UTSWi001-A
(FA1)
Donor diseases:
Friedreich Ataxia
UPITTi004-A
(CN090 C5A5J2)
Donor diseases:
Sickle cell anemia
UPITTi004-B
(CN090 C1B5B5)
Donor diseases:
Sickle cell anemia
BGUi001-A
(BGU01iPORhet)
Donor diseases:
P450 Oxidoreductase Deficiency
BGUi002-A
(BGU02iPOR)
Donor diseases:
P450 Oxidoreductase Deficiency
BGUi003-A
(BGU03iPOR)
Donor diseases:
P450 Oxidoreductase Deficiency
Last update 20th November 2020
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Provider

Generator Vrije Universiteit Amsterdam (VU)

External Databases

Cellosaurus CVCL_ZB12
BioSamples SAMEA7762116
Wikidata Q98134634

General Information

* Is the cell line readily obtainable for third parties?
No

Donor Information

General Donor Information

Sex male

Phenotype and Disease related information (Donor)

Diseases A disease was diagnosed.
Synonyms
  • Schizophrenia
  • schizophrenia
  • Schizophrenia, unspecified

External Databases (Donor)

BioSamples SAMEA7762117

Ethics

Has informed consent been obtained from the donor of the embryo/tissue from which the pluripotent stem cells have been derived? Yes
Was the consent voluntarily given? Yes
Has the donor been informed that participation will not directly influence their personal treatment? Yes
Can you provide us with a copy of the Donor Information Sheet provided to the donor? Yes
Do you (Depositor/Provider) hold the original Donor Consent Form? Yes
Please indicate whether the data associated with the donated material has been pseudonymised or anonymised. pseudonymised
Does consent explicitly allow the derivation of pluripotent stem cells? Yes
Does consent prevent CELLS DERIVED FROM THE DONATED BIOSAMPLE from being made available to researchers anywhere in the world? Yes
How may genetic information associated with the cell line be accessed? Controlled Access
Will the donor expect to receive financial benefit, beyond reasonable expenses, in return for donating the biosample? No
Has a favourable opinion been obtained from a research ethics committee, or other ethics review panel, in relation to the Research Protocol including the consent provisions? Yes
Name of accrediting authority involved? Regional ethics board in Stockholm
Approval number 2011-324-31 and 2012/214-32
Has a favourable opinion been obtained from a research ethics committee, or other ethics review panel, in relation to the PROPOSED PROJECT, involving use of donated embryo/tissue or derived cells? Yes
Name of accrediting authority involved? Regional ethics board in Stockholm
Approval number 2011-324-31 and 2012/214-32
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?

hIPSC Derivation

General

Source cell type
Synonyms
  • fibroblast
  • Fibroblasts
  • Fibroblast
  • FIBROBLAST
show more synonyms

Reprogramming method

Vector type Non-integrating
Vector Episomal

Vector free reprogramming

Other

Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

Culture Conditions

Medium TeSR™ E8™

Characterisation

Analysis of Undifferentiated Cells
Marker Expressed Immunostaining RT-PCR Flow Cytometry Enzymatic Assay Expression Profiles
SOX2
Yes
POU5F1 (OCT-4)
Yes
Pluripotency Score Novelty Score
25,29 1,67
Morphology pictures

Genotyping

Karyotyping (Cell Line)

Has the cell line karyotype been analysed?
No

Other Genotyping (Cell Line)