WIBRe001-A-4

WIBR3_PRKN_X3DEL_B1-3

General

Cell Line

hPSCreg name WIBRe001-A-4
Cite as:
WIBRe001-A-4 (RRID:CVCL_C7VP)
Alternative name(s)
WIBR3_PRKN_X3DEL_B1-3
Cell line type Human embryonic stem cell (hESC)
Similar lines No similar lines found.
Last update 13th December 2024
Notes Internal experimental control(s) were generated undergoing the same experimental procedure and are registered as WIBRe001-A-35 and WIBRe001-A-36.
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Provider

Generator University of California, Berkeley (CAL)
Distributors

External Databases

BioSamples SAMEA114295604
Cellosaurus CVCL_C7VP
Wikidata Q123033910

General Information

Publications
* Is the cell line readily obtainable for third parties?
Yes
Research use: allowed
Clinical use: not allowed
Commercial use: not allowed
Subclone of

Donor Information

General Donor Information

Sex female
Ethnicity unknown

Phenotype and Disease related information (Donor)

Diseases No disease was diagnosed.
Family history no
Is the medical history available upon request? no
Is clinical information available? no

Other Genotyping (Donor)

Is there genome-wide genotyping or functional data available?
No

External Databases (Donor)

BioSamples SAMEA104129930

Ethics

Also have a look at the ethics information for the parental line WIBRe001-A .

hESC Derivation

The source cell information can be found in the parental cell line WIBRe001-A.

Culture Conditions

Medium Other medium:
Base medium: DMEM/F12
Main protein source: Fetal bovine serum
Serum concentration: 15 %

Characterisation

Analysis of Undifferentiated Cells
Marker Expressed Immunostaining RT-PCR Flow Cytometry Enzymatic Assay Expression Profiles
Alkaline Phosphatase
Yes
POU5F1 (OCT-4)
Yes
SSEA-4
Yes

Genotyping

Karyotyping (Cell Line)

Has the cell line karyotype been analysed?
Yes
46XX
Karyotyping method: Array CGH

Other Genotyping (Cell Line)

Genetic Modification

Disease/phenotype related modifications
Synonyms
  • Parkinson Disease
  • Parkinson's disease
  • Parkinson's Disease
Genetic modifications
PRKN parkin RBR E3 ubiquitin protein ligase (target)
Isogenic modification
NA
NM_004562.3:c.172-84_412+57del/c.172-1634_412+1936del
NP_004553.2:p.N58Qfs*39/p.N58Qfs*39
Homozygous