ISFi001-A-2

The cell line is not validated yet.

General

Cell Line

hPSCreg name ISFi001-A-2
Cite as:
ISFi001-A-2
Cell line type Human induced pluripotent stem cell (hiPSC)
Similar lines No similar lines found.
Last update 17th December 2024
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Provider

Generator Institute of Medical Genetics (IMG)
Owner Institute of Medical Genetics (IMG)
Derivation country Switzerland

External Databases

BioSamples SAMEA117515742

General Information

* Is the cell line readily obtainable for third parties?
No
Subclone of

Donor Information

General Donor Information

Sex male

Phenotype and Disease related information (Donor)

Diseases No disease was diagnosed.
Family history No
Is the medical history available upon request? No
Is clinical information available? No

Other Genotyping (Donor)

Is there genome-wide genotyping or functional data available?
Yes

External Databases (Donor)

BioSamples SAMEA6703538

Ethics

Also have a look at the ethics information for the parental line ISFi001-A .
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?

hIPSC Derivation

General

The source cell information can be found in the parental cell line ISFi001-A.

Reprogramming method

Vector free reprogramming

Other

Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

Culture Conditions

Characterisation

Analysis of Undifferentiated Cells
Marker Expressed Immunostaining RT-PCR Flow Cytometry Enzymatic Assay Expression Profiles
NANOG
Yes
POU5F1 (OCT-4)
Yes
SOX2
Yes
Differentiation Potency

Genotyping

Karyotyping (Cell Line)

Has the cell line karyotype been analysed?
Yes
46, XY
Karyotyping method: Molecular karyotyping by SNP array
http://

Other Genotyping (Cell Line)

Genetic Modification

Disease/phenotype related modifications
CEP290 gene
Synonyms
  • CPD IV
  • JBTS
  • Joubert syndrome
  • Joubert syndrome type A
  • Joubert-Boltshauser syndrome
  • cerebelloparenchymal disorder IV
  • classic Joubert syndrome
  • pure Joubert syndrome
  • cerebellar vermis agenesis
show more synonyms
Genetic modifications
Gene knock-out
12q21.32
CEP290 homozygous p.(L1787Hfs*12)
CRISPR-associated (CRISPR/Cas) System