BGU03iPOR

General

Cell Line

hPSCreg Name
BGUi003-A
Alternative name(s)
BGU03iPOR
Cell line type Human induced pluripotent stem cell (hiPSC)
Similar lines
BGUi001-A
(BGU01iPORhet)
Donor diseases:
P450 Oxidoreductase Deficiency
BGUi002-A
(BGU02iPOR)
Donor diseases:
P450 Oxidoreductase Deficiency
UNIZARi001-A
(FiPSTK2-2)
Donor's gene variants:
TK2, TK2
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Mitochondrial DNA depletion syndrome, myopathic form
WTSIi658-A
(HPSI0816i-fuuy_3)
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WTSIi405-A
(HPSI0614i-fovu_2)
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WTSIi406-A
(HPSI0614i-mesr_4)
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Bardet-Biedl syndrome
STBCi110-A
(SFC116-03-01)
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CFH
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type 2 diabetes mellitus
age-related macular degeneration
WTSIi407-A
(HPSI0914i-hidy_4)
Donor diseases:
Bardet-Biedl syndrome
WTSIi454-B
(HPSI0516i-iool_4)
Donor diseases:
Usher syndrome
WTSIi531-B
(HPSI0616i-kayf_6)
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Spastic paraplegia
WTSIi414-A
(HPSI0614i-eisk_3)
Donor diseases:
Bardet-Biedl syndrome
WTSIi147-A
(HPSI1013i-mijn_2)
Donor diseases:
Bardet-Biedl syndrome
WTSIi148-A
(HPSI0114i-veui_3)
Donor diseases:
Bardet-Biedl syndrome
WTSIi151-A
(HPSI0414i-fixm_2)
Donor diseases:
Bardet-Biedl syndrome
WTSIi675-A
(HPSI0616i-iuse_5)
Donor diseases:
Spastic paraplegia
WTSIi675-B
(HPSI0616i-iuse_6)
Donor diseases:
Spastic paraplegia
WTSIi152-A
(HPSI0414i-eafb_1)
Donor diseases:
Bardet-Biedl syndrome
WTSIi614-B
(HPSI0616i-rily_1)
Donor diseases:
Spastic paraplegia
WTSIi154-A
(HPSI0414i-lavd_2)
Donor diseases:
Bardet-Biedl syndrome
WTSIi158-A
(HPSI0914i-fuhz_1)
Donor diseases:
Bardet-Biedl syndrome
WTSIi159-A
(HPSI0714i-gibe_2)
Donor diseases:
Bardet-Biedl syndrome
WTSIi161-A
(HPSI0714i-rajk_1)
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Bardet-Biedl syndrome
WTSIi165-A
(HPSI0414i-reng_4)
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Bardet-Biedl syndrome
WTSIi167-A
(HPSI1013i-funy_1)
Donor diseases:
Bardet-Biedl syndrome
WTSIi447-A
(HPSI0416i-zige_5)
Donor diseases:
Usher syndrome
WTSIi450-A
(HPSI0216i-aiid_1)
Donor diseases:
Usher syndrome
WTSIi452-A
(HPSI0115i-xaka_2)
Donor diseases:
Bardet-Biedl syndrome
WTSIi454-A
(HPSI0516i-iool_6)
Donor diseases:
Usher syndrome
WTSIi414-B
(HPSI0614i-eisk_6)
Donor diseases:
Bardet-Biedl syndrome
WTSIi405-B
(HPSI0614i-fovu_5)
Donor diseases:
Bardet-Biedl syndrome
WTSIi458-B
(HPSI0614i-lipl_5)
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Bardet-Biedl syndrome
WTSIi573-A
(HPSI0115i-qaqp_4)
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Bardet-Biedl syndrome
ZZUi030-A
(ZZU-iPS-SPG7-001)
Donor diseases:
Spastic paraplegia type 7
WTSIi576-A
(HPSI0216i-feht_1)
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Usher syndrome
WTSIi402-B
(HPSI0714i-ouzk_4)
Donor diseases:
Bardet-Biedl syndrome
WTSIi465-B
(HPSI0714i-xiry_1)
Donor diseases:
Bardet-Biedl syndrome
WTSIi407-B
(HPSI0914i-hidy_3)
Donor diseases:
Bardet-Biedl syndrome
WTSIi614-A
(HPSI0616i-rily_3)
Donor diseases:
Spastic paraplegia
WTSIi452-B
(HPSI0115i-xaka_1)
Donor diseases:
Bardet-Biedl syndrome
WTSIi573-B
(HPSI0115i-qaqp_5)
Donor diseases:
Bardet-Biedl syndrome
WTSIi450-B
(HPSI0216i-aiid_6)
Donor diseases:
Usher syndrome
WTSIi516-B
(HPSI0216i-iogu_6)
Donor diseases:
Usher syndrome
WTSIi447-B
(HPSI0416i-zige_2)
Donor diseases:
Usher syndrome
UPITTi004-A
(CN090 C5A5J2)
Donor diseases:
Sickle cell anemia
UPITTi004-B
(CN090 C1B5B5)
Donor diseases:
Sickle cell anemia
WTSIi522-B
(HPSI0516i-pews_2)
Donor diseases:
Usher syndrome
WTSIi402-A
(HPSI0714i-ouzk_5)
Donor diseases:
Bardet-Biedl syndrome
Last update 4th February 2021
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Provider

Generator Ben Gurion University of the Negev (BGU)
Owner Ben Gurion University of the Negev (BGU)
Distributors
Derivation country Israel

External Databases

Cellosaurus CVCL_A9XE
BioSamples SAMEA8072994
CLO CLO_0103227
Wikidata Q102113617

General Information

Publications
* Is the cell line readily obtainable for third parties?
Yes
Research use: allowed
Clinical use: not allowed
Commercial use: not allowed

Donor Information

General Donor Information

Sex male
Ethnicity Bedouin

Phenotype and Disease related information (Donor)

Diseases A disease was diagnosed.
P450 Oxidoreductase Deficiency
Synonyms
  • P450 Oxidoreductase Deficiency

Karyotyping (Donor)

Has the donor karyotype been analysed?
Yes
Karyotyping method: G-Banding

External Databases (Donor)

BioSamples SAMEA8152182

Ethics

Has informed consent been obtained from the donor of the embryo/tissue from which the pluripotent stem cells have been derived? Yes
Was the consent voluntarily given? Yes
Has the donor been informed that participation will not directly influence their personal treatment? Yes
Can you provide us with a copy of the Donor Information Sheet provided to the donor? No
Provide contact information of the holder of the original Donor Information Sheet: Prof Eli Hershkovitz, Soroka medical center
Do you (Depositor/Provider) hold the original Donor Consent Form? No
If you do not hold the Donor Consent Form, do you know who does? Yes
Contact information / weblink Prof Eli Hershkovitz, Soroka medical center
Please indicate whether the data associated with the donated material has been pseudonymised or anonymised. anonymised
Does consent explicitly allow the derivation of pluripotent stem cells? Yes
Does consent prevent CELLS DERIVED FROM THE DONATED BIOSAMPLE from being made available to researchers anywhere in the world? No

Does consent permit research by

an academic institution? Yes
a public organisation? Yes
a non-profit company? Yes
a for-profit corporation? No
How may genetic information associated with the cell line be accessed? No information
Will the donor expect to receive financial benefit, beyond reasonable expenses, in return for donating the biosample? No
Has a favourable opinion been obtained from a research ethics committee, or other ethics review panel, in relation to the Research Protocol including the consent provisions? No
Has a favourable opinion been obtained from a research ethics committee, or other ethics review panel, in relation to the PROPOSED PROJECT, involving use of donated embryo/tissue or derived cells? No
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?

hIPSC Derivation

General

Source cell type
Fibroblasts

Reprogramming method

Vector type Non-integrating
Vector Episomal
Is reprogramming vector detectable?
No
Methods used
PCR

Vector free reprogramming

Other

Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

Culture Conditions

Medium Other medium:
Base medium: NutriStem
Main protein source:
Serum concentration: %

Characterisation

Analysis of Undifferentiated Cells
Marker Expressed Immunostaining RT-PCR FACS Enzymatic Assay Expression Profiles
NANOG
Yes
OCT3/4
Yes
SOX2
Yes
SSEA-4
Yes
TRA 1-60
Yes
Differentiation Potency
Endoderm
Ont Id: UBERON_0000925
In vitro spontaneous differentiation
Marker Expressed
AFP
Yes
Morphology
Mesoderm
Ont Id: UBERON_0000926
In vitro spontaneous differentiation
Marker Expressed
ACTA2
Yes
Morphology
Ectoderm
Ont Id: UBERON_0000924
In vitro spontaneous differentiation
Marker Expressed
NEFL
Yes
Morphology

Genotyping

Karyotyping (Cell Line)

Has the cell line karyotype been analysed?
Yes
normal
Passage number: 10
Karyotyping method: G-Banding

Other Genotyping (Cell Line)