SJTUGHi001-A

General

Cell Line

hPSCreg name SJTUGHi001-A
Cite as:
SJTUGHi001-A (RRID:CVCL_D6J9)
Cell line type Human induced pluripotent stem cell (hiPSC)
Similar lines
ESi077-A
(CABi001-A, PRPF31-MiPS4F3)
Donor's gene variants:
PRPF31, PRPF31
Donor diseases:
Retinitis Pigmentosa
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(LUMC0128iCRB01 heterozygote CRISPR corrected isogenic clone 02, iso02LUMC0128iCRB01)
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CRB1, CRB1
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Retinitis Pigmentosa
CABi002-A
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UNEWi001-A
(UNEW001Ai)
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PRPF31
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UNEWi002-A
(UNEW002Ai, PRPF31 AW)
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PRPF31, PRPF31
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UNEWi003-A
(PRPF31-HD)
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Retinitis pigmentosa
WTSIi698-A
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(HPSI1116i-rafd_4)
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CIRMi525-A
(CW70348)
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retinitis pigmentosa
FRIMOi002-A
(RP2_FiPS4F2.2)
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PRPF31
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(HPSI0816i-oemk_6)
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UNEWi004-A
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UNEWi005-A
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(RP.1.H.iPSC.2)
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(CW70323)
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retinitis pigmentosa
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(CW70342)
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retinitis pigmentosa
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(EYS mutation)
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retinitis pigmentosa
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CRB1, CRB1
Donor diseases:
Retinitis Pigmentosa
CIRMi531-A
(CW70356)
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retinitis pigmentosa
LUMCi056-A
(CRB1 patient 128 compound heterozygous c.2843G>A p.(Cys948Tyr) and c.3122T>C p.(Met1041Thr), LUMC0128iCRB01)
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CRB1, CRB1
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Retinitis Pigmentosa
CIRMi542-A
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retinitis pigmentosa
IDVi001-A
(iPS-NR2E3-86)
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Retinitis pigmentosa
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(HPSI1116i-wakr_3)
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Retinitis pigmentosa
NUIGi027-A
(RP001C8)
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Retinitis Pigmentosa
NUIGi028-A
(RP002C12)
Donor diseases:
Retinitis Pigmentosa
NUIGi029-A
(RP003C12)
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Retinitis Pigmentosa
WTSIi463-B
(HPSI0716i-yibs_3)
Donor diseases:
Retinitis pigmentosa
RIi009-A
(RP2.H.iPSC.3)
Donor diseases:
Retinitis pigmentosa
Last update 6th March 2024
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Provider

Generator Shanghai General Hospital (SJTUGH)

External Databases

BioSamples SAMEA115376234
Cellosaurus CVCL_D6J9

General Information

Publications
* Is the cell line readily obtainable for third parties?
No

Donor Information

General Donor Information

Sex female

Phenotype and Disease related information (Donor)

Diseases A disease was diagnosed.
The donor is a carrier of a disease-associated mutation and affected.
Synonyms
  • Retinitis Pigmentosa

External Databases (Donor)

BioSamples SAMEA115377470

Ethics

Has informed consent been obtained from the donor of the embryo/tissue from which the pluripotent stem cells have been derived? Yes
Was the consent voluntarily given? Yes
Has the donor been informed that participation will not directly influence their personal treatment? Yes
Can you provide us with a copy of the Donor Information Sheet provided to the donor? Yes
Do you (Depositor/Provider) hold the original Donor Consent Form? Yes
Please indicate whether the data associated with the donated material has been pseudonymised or anonymised. pseudonymised
Does consent explicitly allow the derivation of pluripotent stem cells? Yes
Does consent prevent CELLS DERIVED FROM THE DONATED BIOSAMPLE from being made available to researchers anywhere in the world? No
How may genetic information associated with the cell line be accessed? No information
Will the donor expect to receive financial benefit, beyond reasonable expenses, in return for donating the biosample? No
Has a favourable opinion been obtained from a research ethics committee, or other ethics review panel, in relation to the Research Protocol including the consent provisions? Yes
Name of accrediting authority involved? Ethical Committee of Shanghai general hospital
Approval number 2018科154-2
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?

hIPSC Derivation

General

Source cell type
A peripheral blood cell with a single nucleus. This category includes lymphocytes and monocytes.
Synonyms
  • PERIPHERAL BLOOD MONONUCLEAR CELL
  • Peripheral Blood Mononuclear Cell
  • PBMC
Source cell origin
Blood drawn from a limb.
Synonyms
  • Peripheral Blood
  • Peripheral blood

Reprogramming method

Vector type Non-integrating
Vector Episomal

Vector free reprogramming

Other

Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

Culture Conditions

Medium mTeSR™ 1

Characterisation

Analysis of Undifferentiated Cells
Marker Expressed Immunostaining RT-PCR Flow Cytometry Enzymatic Assay Expression Profiles
SSEA-4
Yes
TRA 1-60
Yes
Differentiation Potency
Endoderm
Ont Id: UBERON_0000925
In vitro spontaneous differentiation
Marker Expressed
AFP
Yes
Mesoderm
Ont Id: UBERON_0000926
In vitro spontaneous differentiation
Marker Expressed
TBXT
Yes
Ectoderm
Ont Id: UBERON_0000924
In vitro spontaneous differentiation
Marker Expressed
PAX6
Yes

Genotyping

Karyotyping (Cell Line)

Has the cell line karyotype been analysed?
Yes
46, XX
Passage number: 16
Karyotyping method: G-Banding

Other Genotyping (Cell Line)