SCVI 692

The cell line is not validated yet.

General

Cell Line

hPSCreg name SCVIi134-A
Cite as:
SCVIi134-A
Alternative name(s)
SCVI 692
Cell line type Human induced pluripotent stem cell (hiPSC)
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(fIPS_DM1_P1 cl1, iPS19-00072 cl1)
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HADe001-A
(HAD 1)
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CBRCULi015-A
(GM23375-1, GM23375 clone 1)
Donor's gene variants:
DMPK – DM1 protein kinase, DMPK – DM1 protein kinase
Donor diseases:
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ZZUi015-A
(ZZU-iPS-DM1-002)
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myotonic dystrophy type 1
KCLe014-A
(KCL018_MD1)
Donor diseases:
myotonic dystrophy type 1
Last update 23rd February 2026
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Provider

Generator Stanford Cardiovascular Institute (SCVI)
Owner Stanford Cardiovascular Institute (SCVI)
Distributors

External Databases

BioSamples SAMEA116132628

General Information

* Is the cell line readily obtainable for third parties?
Yes
Research use: allowed
Clinical use: not allowed
Commercial use: not allowed

Donor Information

General Donor Information

Sex female
Ethnicity White

Phenotype and Disease related information (Donor)

Diseases A disease was diagnosed.
Synonyms
  • DM1
  • DMPK myotonic dystrophy
  • MD1
  • Steinert disease
  • Steinert myotonic dystrophy syndrome
  • Steinert syndrome
  • dystrophia myotonica
  • myotonic dystrophy caused by mutation in DMPK
  • myotonic dystrophy of Steinert
  • myotonic dystrophy type 1
  • Steinert myotonic dystrophy
  • Steinert's disease
  • dystrophia myotonica 1
  • dystrophia myotonica type 1
  • myotonic dystrophy 1
  • Myotonic Dystrophy
show more synonyms

External Databases (Donor)

BioSamples SAMEA116132629

Ethics

Has informed consent been obtained from the donor of the embryo/tissue from which the pluripotent stem cells have been derived? Yes
Was the consent voluntarily given? Yes
Has the donor been informed that participation will not directly influence their personal treatment? Yes
Can you provide us with a copy of the Donor Information Sheet provided to the donor? No
Do you (Depositor/Provider) hold the original Donor Consent Form? No
If you do not hold the Donor Consent Form, do you know who does? Yes
Please indicate whether the data associated with the donated material has been pseudonymised or anonymised. pseudonymised
Does consent explicitly allow the derivation of pluripotent stem cells? Yes
* Does consent expressly prevent the derivation of pluripotent stem cells? No
* Does consent pertain to a specific research project? No
Does consent prevent CELLS DERIVED FROM THE DONATED BIOSAMPLE from being made available to researchers anywhere in the world? No
How may genetic information associated with the cell line be accessed? Controlled Access
Will the donor expect to receive financial benefit, beyond reasonable expenses, in return for donating the biosample? No
Has a favourable opinion been obtained from a research ethics committee, or other ethics review panel, in relation to the Research Protocol including the consent provisions? No
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?

hIPSC Derivation

General

Source cell type
Human induced pluripotent stem cell.
Synonyms
  • human induced pluripotent stem cell

Reprogramming method

Vector type Non-integrating
Vector Sendai virus
Genes
Is reprogramming vector detectable?
No
Methods used
RT-PCR

Vector free reprogramming

Other

Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

Culture Conditions

Surface coating Matrigel/Geltrex
Medium Other medium:
Base medium: StemMACS iPS-Brew XF
Main protein source:
Serum concentration: %
Supplements
Miltenyi #130-104-368, #130-104-370 %

Characterisation

Analysis of Undifferentiated Cells
Marker Expressed Immunostaining RT-PCR Flow Cytometry Enzymatic Assay Expression Profiles
NANOG
Yes
SOX2
Yes
POU5F1 (OCT-4)
Yes
Morphology pictures
Self-renewal
Positive
Endoderm
Positive
Mesoderm
Positive
Ectoderm score
Positive
Differentiation Potency
Endoderm
Ont Id: UBERON_0000925
In vitro directed differentiation
Mesoderm
Ont Id: UBERON_0000926
In vitro directed differentiation
Ectoderm
Ont Id: UBERON_0000924
In vitro directed differentiation

Genotyping

Karyotyping (Cell Line)

Has the cell line karyotype been analysed?
Yes
46, XX
Passage number: 21

Other Genotyping (Cell Line)