General#

Cell Line

hPSCreg Name UBi001-A-2
Cell line type Human induced pluripotent stem cell (hiPSC)
Last update 30th October 2019
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Provider

Generator University of Barcelona (UB)

External Databases

BioSamples SAMEA6298141

General Information

Publications
* Is the cell line readily obtainable for third parties?
No
Subclone of

Donor Information#

General Donor Information

Sex male

Phenotype and Disease related information (Donor)

Diseases A disease was diagnosed.
Sanfilippo syndrome type C
The donor is not a carrier of a disease-associated mutation and not affected.
Synonyms
  • Mucopolysaccharidosis type 3C
  • MPS3C
  • HGSNAT deficiency
  • Heparan-alpha-glucosaminide N-acetyltransferase deficiency
  • MPSIIIC
  • Mucopolysaccharidosis type IIIC
show more synonyms

Karyotyping (Donor)

Has the donor karyotype been analysed?
Yes
46, XY
Karyotyping method: G-Banding

External Databases (Donor)

BioSamples SAMEA6298140

Ethics#

Also have a look at the ethics information for the parental line UBi001-A .
Is there an MTA available for the cell line? No
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used? Thermo Fisher Scientific
Are you aware of any constraints on the use or distribution of the cell line from the owner or any parties identified in the query above? No

hIPSC Derivation#

General

The source cell information can be found in the parental cell line UBi001-A.

Reprogramming method

Vector type None

Vector free reprogramming

Other

Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

Culture Conditions#

Medium mTeSR™ 1

Characterisation#

No characterisation data could be found for this subclone. Please open parental cell line UBi001-A

Genotyping#

Karyotyping (Cell Line)

Has the cell line karyotype been analysed?
Yes
46, XY
Karyotyping method: G-Banding

Other Genotyping (Cell Line)

Genetic Modification#

Disease/phenotype related modifications
Sanfilippo syndrome type C
Synonyms
  • Mucopolysaccharidosis type 3C
  • MPS3C
  • HGSNAT deficiency
  • Heparan-alpha-glucosaminide N-acetyltransferase deficiency
  • MPSIIIC
  • Mucopolysaccharidosis type IIIC
show more synonyms
Genetic modifications
HGSNAT (target)
Gene knock-out
8p11.2-11.1
CRISPR-associated (CRISPR/Cas) System