FDITBRi002-A

General

Cell Line

hPSCreg name FDHSi002-A
Cite as:
FDHSi002-A (RRID:CVCL_D0EX)
Alternative name(s)
FDITBRi002-A
Cell line type Human induced pluripotent stem cell (hiPSC)
Similar lines
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Parkinson Disease
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obsolete_Parkinson's disease
SUSMi005-A-2
(SNCA3X 1KO C2, SNCA3X 1KO C1)
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obsolete_Parkinson's disease
SUSMi005-A-3
(SNCA3X 2KO C1, SNCA3X 2KO C2)
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obsolete_Parkinson's disease
SUSMi005-A-4
(SNCA3X 3KO C1, SNCA3X 3KO C2)
Donor diseases:
obsolete_Parkinson's disease
SUSMi005-A-5
(SNCA3X 4KO C1, SNCA3X 4KO C2)
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obsolete_Parkinson's disease
LCSBi011-A-1
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LCSBi001-A
(VPS35 1_2)
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obsolete_Parkinson's disease
LCSBi013-A
(GL2)
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EDi001-A-1
(AST22-C, AST23-C)
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SNCA, SNCA
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Parkinson disease
EDi001-A-2
(AST23-1KO-3, AST22-1KO-3, AST-23_SCAKO Clone 3, AST-22_SNCAKO Clone 3)
Donor's gene variants:
SNCA, SNCA, SNCA, SNCA
Donor diseases:
Parkinson disease
EDi001-A-3
(AST23_SNCAKO Clone 1, AST22-1KO-1, AST23-1KO-1, AST22_SNCAKO Clone 1)
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SNCA, SNCA, SNCA, SNCA
Donor diseases:
Parkinson disease
EDi001-A-4
(AST22-2KO-6, AST23_SNCAKO Clone 6, AST22_SNCAKO Clone 6, AST23-2KO-6)
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SNCA, SNCA, SNCA, SNCA
Donor diseases:
Parkinson disease
MPIi003-A-1
(IM2GC, L2-2GC)
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obsolete_Parkinson's disease
EDi001-B-1
(AST18-7A)
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SNCA
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Parkinson disease
EDi001-B-2
(AST18-7B)
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SNCA
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Parkinson disease
EDi001-B-3
(AST18-5D)
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SNCA
Donor diseases:
Parkinson disease
EDi001-B-4
(AST18-6A)
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SNCA
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Parkinson disease
EDi001-A-5
(AST23-2KO-II8B)
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SNCA
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LCPHi003-A
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LRP10
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UMi036-A
(ND34263)
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ZZUi027-A
(ZZU-iPS-PD-RAB39b-002)
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STBCi004-B-1
(SFC832-03-06 LRRK2WT/WT C47)
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LRRK2
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Parkinson disease
STBCi320-A
(SFC031-03-03)
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STBCi295-B
(SFC847-03-08)
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(GBA-002-C3)
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(GBA-003-C8)
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GBA
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DANi005-A
(LRRK2-GBA-005-C1)
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GBA, LRRK2
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DANi007-A
(PINK1-007-C1)
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PINK1
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(SNCA-008-C6)
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SNCA
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GBA
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obsolete_Parkinson's disease
GIBHi003-A
(PINK1-I368N-C2)
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PINK1
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Parkinson Disease
ICGi015-B-1
(m6.7pCyto-17)
Donor diseases:
Parkinson Disease
ICGi015-B-2
(m6.7pCyto-21)
Donor diseases:
Parkinson Disease
ICGi015-B-3
(m6.7pCyto-24)
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Parkinson Disease
OSRi001-A
(PD-OPA1-A495V#72)
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DANi004-A
(PRKN-004-C1)
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Parkinson Disease
DANi006-F
(GBA-006-C6)
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GBA
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Parkinson Disease
DANi010-A
(GBA-010-C1)
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GBA
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Parkinson Disease
ICGi034-A-1
(PD30-XBP-RFP-6, PD30-4-7-XBP-RFP-6)
Donor diseases:
obsolete_Parkinson's disease
DANi011-A
(LRRK2-011-C1)
Donor's gene variants:
LRRK2
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Parkinson Disease
LCSBi009-A
(RHOT1_R272Q_clone1_PD)
Donor diseases:
Parkinson Disease
ICGi034-A-2
(PD30-4-7-XBP-RFP-51, PD30-XBP-RFP-51)
Donor diseases:
obsolete_Parkinson's disease
LCSBi010-A
(RHOT1_R450C_clone5_PD)
Donor diseases:
Parkinson Disease
Last update 27th July 2023
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Provider

Generator Huashan Hospital of Fudan University (FDHS)

External Databases

BioSamples SAMEA114184886
Cellosaurus CVCL_D0EX
Wikidata Q123031276

General Information

Publications
* Is the cell line readily obtainable for third parties?
No

Donor Information

General Donor Information

Sex male

Phenotype and Disease related information (Donor)

Diseases A disease was diagnosed.
The donor is a carrier of a disease-associated mutation and affected.

External Databases (Donor)

BioSamples SAMEA114184885

Ethics

Has informed consent been obtained from the donor of the embryo/tissue from which the pluripotent stem cells have been derived? Yes
Was the consent voluntarily given? Yes
Has the donor been informed that participation will not directly influence their personal treatment? Yes
Can you provide us with a copy of the Donor Information Sheet provided to the donor? No
Please provide contact information of the holder of the original Donor Information Sheet. ys2504@sina.com
Do you (Depositor/Provider) hold the original Donor Consent Form? Yes
Please indicate whether the data associated with the donated material has been pseudonymised or anonymised. anonymised
Does consent explicitly allow the derivation of pluripotent stem cells? Yes
Does consent prevent CELLS DERIVED FROM THE DONATED BIOSAMPLE from being made available to researchers anywhere in the world? Yes
How may genetic information associated with the cell line be accessed? No information
Will the donor expect to receive financial benefit, beyond reasonable expenses, in return for donating the biosample? No
Has a favourable opinion been obtained from a research ethics committee, or other ethics review panel, in relation to the Research Protocol including the consent provisions? Yes
Name of accrediting authority involved? Institutional Review Board of Huashan Hospital, Fudan University
Approval number 2011-174-5
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?

hIPSC Derivation

General

Source cell type
Synonyms
  • fibroblast
  • Fibroblasts
  • Fibroblast
  • FIBROBLAST
show more synonyms

Reprogramming method

Vector type Non-integrating
Vector Episomal
Is reprogramming vector detectable?
No
Methods used
PCR
Files and images showing reprogramming vector expressed or silenced
Vector map

Vector free reprogramming

Other

Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

Culture Conditions

Surface coating Matrigel/Geltrex
Feeder cells
No
Passage method Enzyme-free cell dissociation
EDTA
Medium Other medium:
Base medium: NutriStem® hPSC XF
Main protein source: Albumine
Serum concentration: 0 %

Characterisation

Analysis of Undifferentiated Cells
Marker Expressed Immunostaining RT-PCR Flow Cytometry Enzymatic Assay Expression Profiles
NANOG
Yes
SSEA-4
Yes
POU5F1 (OCT-4)
Yes
TRA 1-60
Yes
Differentiation Potency
Endoderm
Ont Id: UBERON_0000925
In vitro directed differentiation
Marker Expressed
FOXA2
Yes
Mesoderm
Ont Id: UBERON_0000926
In vitro directed differentiation
Marker Expressed
brachyury
Yes
Ectoderm
Ont Id: UBERON_0000924
In vitro directed differentiation
Marker Expressed
PAX6
Yes

Genotyping

Karyotyping (Cell Line)

Has the cell line karyotype been analysed?
Yes
G banding

Other Genotyping (Cell Line)