UKERiPX7-R1-001

The cell line is not validated yet.

General

Cell Line

hPSCreg name UKERi003-A
Cite as:
UKERi003-A (RRID:CVCL_VF23)
Alternative name(s)
UKERiPX7-R1-001
Cell line type Human induced pluripotent stem cell (hiPSC)
Similar lines
LCSBi012-A-1
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Parkinson's Disease
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Parkinson's Disease
SUSMi005-A-1
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obsolete_Parkinson's disease
SUSMi005-A-2
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obsolete_Parkinson's disease
SUSMi005-A-3
(SNCA3X 2KO C1, SNCA3X 2KO C2)
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obsolete_Parkinson's disease
SUSMi005-A-4
(SNCA3X 3KO C1, SNCA3X 3KO C2)
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obsolete_Parkinson's disease
SUSMi005-A-5
(SNCA3X 4KO C1, SNCA3X 4KO C2)
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obsolete_Parkinson's disease
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EDi001-A-1
(AST22-C, AST23-C)
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SNCA, SNCA
Donor diseases:
Parkinson disease
EDi001-A-2
(AST23-1KO-3, AST22-1KO-3, AST-23_SCAKO Clone 3, AST-22_SNCAKO Clone 3)
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SNCA, SNCA, SNCA, SNCA
Donor diseases:
Parkinson disease
EDi001-A-3
(AST23_SNCAKO Clone 1, AST22-1KO-1, AST23-1KO-1, AST22_SNCAKO Clone 1)
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SNCA, SNCA, SNCA, SNCA
Donor diseases:
Parkinson disease
EDi001-A-4
(AST22-2KO-6, AST23_SNCAKO Clone 6, AST22_SNCAKO Clone 6, AST23-2KO-6)
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SNCA, SNCA, SNCA, SNCA
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Parkinson disease
UOXFi003-A
(MK088-1)
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GBA1
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UOXFi003-C
(MK088-7)
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GBA1
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Parkinson disease
MPIi003-A-1
(IM2GC, L2-2GC)
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obsolete_Parkinson's disease
EDi001-B-1
(AST18-7A)
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SNCA
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Parkinson disease
EDi001-B-2
(AST18-7B)
Donor's gene variants:
SNCA
Donor diseases:
Parkinson disease
EDi001-B-3
(AST18-5D)
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SNCA
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Parkinson disease
EDi001-B-4
(AST18-6A)
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SNCA
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Parkinson disease
EDi001-A-5
(AST23-2KO-II8B)
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SNCA
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Parkinson disease
UOXFi010-C
(JR023-5)
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Parkinson disease
STBCi004-B-1
(SFC832-03-06 LRRK2WT/WT C47)
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LRRK2
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Parkinson disease
FINi002-A
(FI.CPLT.PRKN.R275W+del_e8.PK006)
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PRKN
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Parkinson's Disease
LCSBi009-A-1
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LCSBi010-A-1
(RHOT1_R450C_clone6_IsogenicControl)
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Parkinson's Disease
SHEHDNi002-A
(KY03AP)
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LRRK2, DNAJC6
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EDi001-A
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SNCA, SNCA, SNCA
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UOXFi001-A
(MK071-1)
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GBA1
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Parkinson disease
UOXFi001-B
(MK071-3)
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GBA1
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Parkinson disease
UOXFi001-C
(MK071-5)
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GBA1
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Parkinson disease
UOXFi001-D
(MK071-6)
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GBA1
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Parkinson disease
EDi001-B
(AST18)
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SNCA
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Parkinson disease
UOXFi007-A
(MK002-4)
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LRRK2
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Parkinson disease
UOXFi008-A
(MK144-1)
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LRRK2
Donor diseases:
Parkinson disease
ICGi015-B-1
(m6.7pCyto-17)
Donor diseases:
Parkinson's Disease
ICGi015-B-2
(m6.7pCyto-21)
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Parkinson's Disease
ICGi015-B-3
(m6.7pCyto-24)
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Parkinson's Disease
UKERi002-A
(UKERiM89-R1-006)
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obsolete_Parkinson's disease
ICGi034-A-1
(PD30-XBP-RFP-6, PD30-4-7-XBP-RFP-6)
Donor diseases:
obsolete_Parkinson's disease
ICGi034-A-2
(PD30-4-7-XBP-RFP-51, PD30-XBP-RFP-51)
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obsolete_Parkinson's disease
STBCi090-B
(SFC867-04-12)
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Parkinson disease
PNUSCRi001-A
(GBA PD iPSC7)
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GBA
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Parkinson's Disease
LCSBi008-A
(delP, DJ-1-delP)
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Parkinson's Disease
PNUSCRi002-A
(GBA PD iPSC9)
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GBA
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Parkinson's Disease
ICGi042-A
(PD12-4Lm)
Donor's gene variants:
LRRK2, PINK1
Donor diseases:
Parkinson's Disease
ICGi042-B
(PD12-5Lm)
Donor's gene variants:
LRRK2, PINK1
Donor diseases:
Parkinson's Disease
ICGi042-C
(PD12-6Lm)
Donor's gene variants:
LRRK2, PINK1
Donor diseases:
Parkinson's Disease
STBCi005-B
(SFC833-03-05)
Donor's gene variants:
LRRK2
Donor diseases:
Parkinson disease
STBCi005-C
(SFC833-03-14)
Donor's gene variants:
LRRK2
Donor diseases:
Parkinson disease
Last update 22nd May 2019
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Provider

Generator Universitätsklinikum Erlangen (UKER)

External Databases

BioSamples SAMEA104010909
Cellosaurus CVCL_VF23
Wikidata Q54990282

General Information

* Is the cell line readily obtainable for third parties?
No

Donor Information

General Donor Information

Sex male

Phenotype and Disease related information (Donor)

Diseases A disease was diagnosed.
Synonyms
  • Parkinson's syndrome
  • Parkinsons
  • Primary Parkinsonism
  • Parkinsons disease
  • Parkinson disease
  • Parkinson's disease (disorder)
  • Parkinson's disease NOS
  • Parkinson Disease, Idiopathic
  • PARKINSON DIS
  • IDIOPATHIC PARKINSONS DIS
  • PARKINSON DIS IDIOPATHIC
  • Parkinsonism, Primary
  • Parkinson's Disease, Lewy Body
  • IDIOPATHIC PARKINSON DIS
  • Idiopathic PD
  • Idiopathic Parkinson Disease
  • Lewy Body Parkinson's Disease
  • Parkinsonian disorder
  • LEWY BODY PARKINSON DIS
  • Parkinson's
  • Idiopathic Parkinson's Disease
  • Parkinson's disease NOS (disorder)
  • Lewy Body Parkinson Disease
  • PARKINSONS DIS IDIOPATHIC
  • PARKINSONS DIS
  • Parkinson's Disease, Idiopathic
  • Parkinson syndrome
  • PARKINSONS DIS LEWY BODY
  • Paralysis agitans
show more synonyms

External Databases (Donor)

BioSamples SAMEA104010910

Ethics

Has informed consent been obtained from the donor of the embryo/tissue from which the pluripotent stem cells have been derived? Yes
Was the consent voluntarily given? Yes
Has the donor been informed that participation will not directly influence their personal treatment? Yes
Can you provide us with a copy of the Donor Information Sheet provided to the donor? Yes
Provide contact information of the holder of the original Donor Information Sheet:
Do you (Depositor/Provider) hold the original Donor Consent Form? Yes
Contact information / weblink
Alternatives to consent
Alternative consent approval number
Please indicate whether the data associated with the donated material has been pseudonymised or anonymised. pseudonymised
Does consent explicitly allow the derivation of pluripotent stem cells? Yes
Does consent expressly prevent the derivation of pluripotent stem cells? No
Details on restriction to research project
Does consent prevent CELLS DERIVED FROM THE DONATED BIOSAMPLE from being made available to researchers anywhere in the world? No
How may genetic information associated with the cell line be accessed? No information
Will the donor expect to receive financial benefit, beyond reasonable expenses, in return for donating the biosample? No
Please describe how access is provided:
Contact data, institution, or website:
Has a favourable opinion been obtained from a research ethics committee, or other ethics review panel, in relation to the Research Protocol including the consent provisions? Yes
Name of accrediting authority involved? Research Ethics Committee Friedrich-Alexander University Erlangen-Nürnberg
Approval number 4120
Has a favourable opinion been obtained from a research ethics committee, or other ethics review panel, in relation to the PROPOSED PROJECT, involving use of donated embryo/tissue or derived cells? No
Name of accrediting authority involved?
Approval number
Please describe:
Further constraints on use
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?
Constraints for use or distribution

hIPSC Derivation

General

Source cell type
Any skin fibroblast that is part of some dermis.
Source cell origin
Any portion of the organ that covers that body and consists of a layer of epidermis and a layer of dermis.
Synonyms
  • portion of skin
  • region of skin
  • skin
  • skin region
  • skin zone
show more synonyms

Reprogramming method

Vector type Integrating

Vector free reprogramming

Other

Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

Culture Conditions

Medium mTeSR™ 1

Characterisation

Analysis of Undifferentiated Cells
Marker Expressed Immunostaining RT-PCR Flow Cytometry Enzymatic Assay Expression Profiles
NANOG
Yes
POU5F1 (OCT-4)
Yes
TRA 1-60
Yes

Genotyping

Karyotyping (Cell Line)

Has the cell line karyotype been analysed?
Yes
46XY

Other Genotyping (Cell Line)