BIONi037-A-2

BIONi037-A ApoE2/2 #M10-7

General#

Cell Line

hPSCreg Name BIONi037-A-2
Alternative name(s)
BIONi037-A ApoE2/2 #M10-7
Cell line type Human induced pluripotent stem cell (hiPSC)
Last update 21st September 2017

Provider

Generator Bioneer (BSC)
Contact:
Bioneer (BION)
Owner Bioneer (BION)
Distributors EBiSC (BIONi037-A-2 on EBiSC)
Derivation country Denmark

External Databases

BioSamples SAMEA104235612

General Information

Is the cell line available in principle? Available, without restrictions
Subclone of

Donor Information#

General Donor Information

Sex female
Ethnicity caucasian

Phenotype and Disease related information (Donor)

Diseases No disease was diagnosed.

Other Genotyping (Donor)

Is there genome-wide genotyping or functional data available?
No

Donor Relations

Other cell lines of this donor

External Databases (Donor)

BioSamples SAMEA104026331

Ethics#

We are currently revising the public data view for cell lines registered in hPSCreg. This section will be visible again in the next weeks.

hIPSC Derivation#

General

Primary cell type Fibroblast of dermis
Fibroblast of dermis in the OLS
Primary cell line name
Primary cell line vendor

Reprogramming method

Vector type Non-integrating
Vector Episomal
Genes
Is reprogramming vector detectable?
No
Methods used
PCR

Vector free reprogramming

Type of used vector free reprogramming factor(s)
None

Other

Selection criteria for clones Morphology
Derived under xeno-free conditions
No
Derived under GMP?
Yes
Available as clinical grade?
No

Culture Conditions#

Surface coating Matrigel/Geltrex
Medium Essential 8™

Characterisation#

Analysis of Undifferentiated Cells
Morphology pictures

Microbiology / Virus Screening

HIV 1 Negative
HIV 2 Negative
Hepatitis B Negative
Hepatitis C Negative
Mycoplasma Negative

Certificate of Analysis

Is there a certificate of analysis available?
No

Genotyping#

Karyotyping (Cell Line)

Has the cell line karyotype been analysed?
Yes
46 XY
Karyotyping method: G-Banding

Other Genotyping (Cell Line)

Genetic Modification#

Genetic Modifications (other than for reprogramming)

Disease/phenotype related modifications
Alzheimers disease
Synonyms
  • Disease, Alzheimer
  • Dementia in Alzheimer's disease, unspecified (disorder)
  • Presenile Alzheimer Dementia
  • ALZHEIMERS DIS
  • Alzheimers
  • DAT - Dementia Alzheimer's type
  • Dementia in Alzheimer's disease
  • Alzheimer's disease, NOS
  • Alzheimer Dementia, Presenile
  • Dementia, Alzheimer Type
  • Alzheimer Dementia
  • Alzheimer's Dementia
  • Alzheimer's
  • Dementia, Presenile
  • [X]Dementia in Alzheimer's disease (disorder)
  • ALZHEIMER DIS
  • AD
  • [X]Dementia in Alzheimer's disease
  • AD - Alzheimer's disease
  • Disease, Alzheimer's
  • Alzheimer Disease
  • Dementia, Presenile Alzheimer
  • Alzheimer Type Dementia
  • Dementia in Alzheimer's disease (disorder)
  • Alzheimer's disease (disorder)
  • Alzheimers Dementia
  • Dementia of the Alzheimer's type
  • sporadic Alzheimer's disease
show more synonyms
Genetic modifications
Isogenic modification
19q13.32
rs7412 (T/T); rs429358 (T/T)
112Cys, 158Cys
Homozygous
The bases at both SNPs rs7412 and rs429358 were changed to a T
Genetic modifications not related to a disease