LUMCi004-A-5

LU99_SCN5A-R282H_cis

General

Cell Line

hPSCreg name LUMCi004-A-5
Cite as:
LUMCi004-A-5 (RRID:CVCL_E4H6)
Alternative name(s)
LU99_SCN5A-R282H_cis
Cell line type Human induced pluripotent stem cell (hiPSC)
Similar lines No similar lines found.
Last update 30th September 2024
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Provider

Generator Leiden University Medical Center (LUMC)

External Databases

BioSamples SAMEA116100393
Cellosaurus CVCL_E4H6

General Information

* Is the cell line readily obtainable for third parties?
Yes
Research use: allowed
Clinical use: not allowed
Commercial use: not allowed
Subclone of

Donor Information

General Donor Information

Sex female
Ethnicity caucasian

Phenotype and Disease related information (Donor)

Diseases No disease was diagnosed.
Family history No
Is the medical history available upon request? No
Is clinical information available? No

Other Genotyping (Donor)

Is there genome-wide genotyping or functional data available?
No

Donor Relations

Other cell lines of this donor

External Databases (Donor)

BioSamples SAMEA5032583

Ethics

Also have a look at the ethics information for the parental line LUMCi004-A .
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?

hIPSC Derivation

General

The source cell information can be found in the parental cell line LUMCi004-A.

Reprogramming method

Vector type None

Vector free reprogramming

Type of used vector free reprogramming factor(s)
mRNA

Other

Derived under xeno-free conditions
Unknown
Derived under GMP?
No
Available as clinical grade?
No

Culture Conditions

Medium Other medium:
Base medium: StemFlex Medium
Main protein source: Fetal bovine serum
Serum concentration: %

Characterisation

Microbiology / Virus Screening

Mycoplasma Negative

Genotyping

Karyotyping (Cell Line)

Has the cell line karyotype been analysed?
Yes
Normal, 46, XX
Karyotyping method: G-Banding

Other Genotyping (Cell Line)

Genetic Modification

Disease/phenotype related modifications
Synonyms
  • Right Bundle Branch Block, ST Segment Elevation, and Sudden Death Syndrome
  • Brugada Syndrome
Genetic modifications
SCN5A (target)
Variant
3p21