LU99_SCN5A-R282H_cis
LUMCi004-A-5
General
Cell Line |
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| hPSCreg name | LUMCi004-A-5 |
| Cite as: | LUMCi004-A-5 (RRID:CVCL_E4H6) |
| Alternative name(s) |
LU99_SCN5A-R282H_cis
|
| Cell line type | Human induced pluripotent stem cell (hiPSC) |
| Similar lines |
LUMCi004-A-6 (LU99_SCN5A-R282H_trans) LUMCi004-A (LUMC0099iCTRL04) UCSDi001-A-2 (LQT3_35_iPSC_P15, UCSD243i-LQT3-1) UCSDi001-A-3 (LQT3_4_28_Homo_52_iPSC_P15, UCSD244i-LQT3-2) UCSDi001-A-5 (UCSD246i-CNTL-2, T036_SNP1_Het_3_iPSC_P16_R01) CBRCULi016-A-1 (SCN5A p.R219H-14C-ISO) Donor's gene variants: SCN5A Donor diseases: dilated cardiomyopathy LUMCi004-A-1 (LU99_AAVS1-bxb-v2) LUMCi004-A-2 (LU99_CLYBL-bxb-v2) LUMCi004-A-8 (LU99 CLYBL-Bxb-v3_Dual, LUMC0099iCLYBL-06) LUMCi004-A-7 (LU99-04_AAVS-bxb-dual) LUMCi004-A-3 (LUMCi099_XPA_B8) LUMCi004-A-4 (LUMCi099_XPC_D10) LUMCi004-D (LUMC0289iCTRL07, LUMC0289iCTRL10, LUMC0289iCTRL12) LUMCi004-B (LUMC0030iCTRL12) LUMCi004-C (LUMC0031iCTRL08) BBANTWi012-A-5 (iPSC_F199001_C3_CRISPR_CACNA1C_T330M_HMZ_C6) BBANTWi012-A-6 (iPSC_F199001_C3_CRISPR_CACNA1C_T330M_HTZ_C11.2) UCSDi001-A-1 (UCSD242i-LQT1-1, LQT1_2_5_iPSC_P17) UCSDi001-A-4 (UCSD245i-CNTL-1, T036_SNP1_Het_1_iPSC_P15_R01) NUIGi038-B-1 (CR.LQTH002Cx-A17) NUIGi038-B-2 (CR.LQTH002Cx-A21) NUIGi038-B-3 (CR.LQTH002Cx-3A15) NUIGi038-B-4 (CR.LQTH002Cx-3A18) WAe009-A-62 (KCNQ1 KO) |
| Last update | 30th September 2024 |
| User feedback | |
Provider |
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| Generator | Leiden University Medical Center (LUMC) |
External Databases |
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| BioSamples | SAMEA116100393 |
| Cellosaurus | CVCL_E4H6 |
General Information |
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| * Is the cell line readily obtainable for third parties? |
Yes Research use: allowed
Clinical use: not allowed
Commercial use: not allowed
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| Subclone of | |
Donor Information
General Donor Information |
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| Sex | female |
| Ethnicity | caucasian |
Phenotype and Disease related information (Donor) |
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| Diseases | No disease was diagnosed.
|
| Family history | No |
| Is the medical history available upon request? | No |
| Is clinical information available? | No |
Other Genotyping (Donor) |
|
| Is there genome-wide genotyping or functional data available? |
No
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Donor Relations |
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| Other cell lines of this donor | |
External Databases (Donor) |
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| BioSamples | SAMEA5032583 |
Ethics
Also have a look at the ethics information for the parental line
LUMCi004-A
.
| For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used? |
hIPSC Derivation
General |
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The source cell information can be found in the parental cell line
LUMCi004-A.
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Reprogramming method |
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| Vector type | None |
Vector free reprogramming |
|
| Type of used vector free reprogramming factor(s) |
mRNA
|
Other |
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| Derived under xeno-free conditions |
Unknown |
| Derived under GMP? |
No |
| Available as clinical grade? |
No |
Culture Conditions
| Medium |
Other medium:
Base medium: StemFlex Medium
Main protein source: Fetal bovine serum Serum concentration: % |
Characterisation
Microbiology / Virus Screening |
|
| Mycoplasma | Negative |
Genotyping
Karyotyping (Cell Line) |
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| Has the cell line karyotype been analysed? |
Yes
Normal, 46, XX
Karyotyping method:
G-Banding
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Other Genotyping (Cell Line) |
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Genetic Modification
| Disease/phenotype related modifications |
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