Belgium

Legal status	VERY PERMISSIVE
Key organization	(NL) Federale Commissie voor medisch en wetenschappelijk onderzoek op Embryo’s in-vitro (FCE) (FR) Commission Fédérale de la recherche médicale et scientifique sur les Embryons in-vitro (CFE)
Policy	Research on hESC in Belgium is allowed and it is regulated by the law for research on in vitro embryos and the law on Medically Assisted Reproduction and the Destination of Supernumerary Embryos and Gametes (2003 and 2007). For hESC derivation, embryos from surplus IVF embryos or, under certain conditions, created for research can be used. Reproductive cloning is prohibited. Commercial use of hESC is forbidden.
Legislation	The main laws covering hESC work is the law of 2003 on research on embryos in vitro. And the law of 2007 on the use of supernumerary embryos from fertility treatments. There is a further refinement on the regulations on how to obtain the embryos for research in 2008.
Legislation Link	http://www.ejustice.just.fgov.be/cgi_loi/change_lg.pl?language=nl&la=N&table_name=wet&cn=2003051131 http://www.ejustice.just.fgov.be/cgi_loi/change_lg.pl?language=fr&la=F&cn=2007070632&table_name=loihttp://www.ejustice.just.fgov.be/cgi_loi/change_lg.pl?language=fr&la=F&cn=2008121944&table_name=loi
Research with embryo	Embryos can be used for research. Creation of embryos for research is permitted, when research can not be achieved using supernumerary embryos. Embryo research is only permitted within 14 days of development.
Embryo donation and cryopreservation	Embryos not implanted can be cryopreserved, destroyed, or donated for research. Donation for research can also happen after a term of 5 years of cryostorage. Patients are required to provide signed informed consent for each of these procedures.

Projects

• A multistage model of thyroid gland function for screening endocrine-disrupting chemicals in a biologically sex-specific manner
• Controlling the timing of human cortical neuron development: from upstream mechanisms to impact on circuit plasticity
• Deciphering the microglia-neuron interactions in human Alzheimer’s disease
• Decoding animal genomes into cell types
• Gamma-secretase allosteric modulation as preventive therapy in Alzheimer’s Disease
• Genetics to understand cellular components of Alzheimer Disease pathogenesis
• Monocyte-to-Macrophage Trajectories After Lung Injury: Spatio-temporal investigation, molecular regulation & functional implications for lung regeneration and immunity.

Provider

• Biobank Antwerpen
• Biobank Antwerpen - Center of Medical Genetics Antwerp
• Ghent University
• Horizon 2020 - European Commission
• Janssen Pharmaceutica
• KU Leuven
• Union chimique belge pharma Sa
• Université Libre de Bruxelles
• Université Libre de Bruxelles - Laboratoire de recherche en reproduction humaine (BIO-PSY-HUM-FERT)
• University of Liège
• University of Liege
• VIB - Center for Molecular Neurology
• VIB - KU Leuven Center for Brain and Disease Research
• Vrije Universiteit Brussel
• Vrije Universiteit Brussel - Department of Embryology and Genetics

hESC Cell lines

• VUBe001-A
• VUBe002-A
• VUBe003-A
• VUBe004-A
• VUBe005-A
• VUBe006-A
• VUBe007-A
• VUBe008-A
• VUBe009-A
• VUBe010-A
• VUBe011-A
• VUBe012-A
• ULBe001-A
• ULBe002-A
• ULBe003-A
• ULBe004-A
• ULBe005-A
• VUBe013-A
• VUBe014-A
• VUBe015-A
• VUBe016-A
• VUBe017-A
• VUBe018-A
• VUBe019-A
• VUBe020-A
• VUBe021-A
• VUBe001-A-1
• WAe009-A-19
• WAe009-A-20
• ESIBIe003-A-6
• VUBe022-A
• VUBe023-A
• VUBe024-A
• VUBe025-A
• VUBe026-A
• VUBe027-A
• VUBe028-A
• VUBe029-A
• VUBe030-A
• VUBe031-A
• VUBe032-A
• VUBe033-A
• WAe025-A-1

hiPSC Cell lines

• ULBi002-A
• ULBi003-A
• SIGi001-A-20
• BBANTWi001-A
• BBANTWi001-B
• BBANTWi001-C
• BBANTWi002-A
• BBANTWi002-B
• BBANTWi002-C
• BBANTWi003-A
• BBANTWi003-B
• BBANTWi003-C
• BBANTWi004-A
• BBANTWi004-B
• BBANTWi004-C
• BBANTWi005-A
• BBANTWi005-B
• BBANTWi005-C
• BBANTWi006-A
• BBANTWi007-A
• ULBi004-A
• BBANTWi008-A
• BBANTWi009-A
• CMGANTi002-A
• CMGANTi003-A
• CMGANTi004-A
• BBANTWi010-A
• KULi003-A
• BBANTWi011-A
• SIGi001-A-21
• SIGi001-A-22
• SIGi001-A-23
• SIGi001-A-24
• CMGANTi005-A
• UGENTi001-A
• CMGANTi006-A
• CMGANTi007-A
• UGENTi001-A-1
• CMGANTi008-A
• SIGi001-A-25
• SIGi001-A-26
• SIGi001-A-27
• SIGi001-A-28
• SIGi001-A-29
• SIGi001-A-30
• UGENTi002-A
• UGENTi002-A-1
• BBANTWi012-A
• BBANTWi012-A-1
• BBANTWi012-A-2
• BBANTWi012-A-3
• BBANTWi012-A-4