Germany
| Legal status | VERY RESTRICTIVE |
|---|---|
| Key organization | Central Ethics Committee for Stem-Cell Research (ZES) |
| Policy | After December 2001, hESCs cannot be created or derived. Cloning is prohibited. hESC research is allowed only if imported cell lines produced before May 1, 2007 are used and only if proven vital for the development of new medical and scientific knowledge. |
| Legislation | Embryo Protection Act and Stem Cell Act |
| Legislation Link | http//bundesrechtjuris.de/eschg/BJNR027460990.html and http://bundesrechtjuris.de/stzg/index.html |
| Embryonic stem cell research policy | Based on the German Act for Protection of Embryos from 1990 the destruction of human embryos is not allowed forbidding also the creation or derivation of hESCs. According the German Stem Cell Act from 2002 and its amendment from 2008, hESC research is allowed only if imported cell lines produced before May 1, 2007 are used and only if proven vital for the development of new medical and scientific knowledge. hESCs can only be used for research purposes (Forschungsvorbehalt) and not for developing a product for the market, i.e. commercialisation. |
| Research with embryo | Embryo research is forbbiden. |
| Embryo donation and cryopreservation | The Embryonic protection Act prohibits embryo donation for research purposes. |
| Somatic cell nuclear transfer | Cloning and Somatic Cell Nuclear Transfer (SCNT) is prohibited. |
Projects
- 2D- and 3D-differentiation of alveolar epithelial cells from hiPSCs
- A human cellular model for bi-allelic MYBPC3 truncating mutation
- A need for speed: mechanisms to coordinate protein synthesis and folding in metazoans
- CaMKII over stimulation in engineered heart tissues (EHTs) made from human induced pluripotent stem cells (hiPSCs): a parameter involved in the immaturity of hiPSC EHTs cardiomyocytes?
- Cardiac open reading frame edition to study cardiomyopathies in pigs
- Cellular modulation by the mitochondrial unfolded protein response
- Designer extracellular matrices to program healthy and diseased cardiac morphogenesis
- Elucidating the interplay between nuclear compartments and transcriptional dynamics during differentiation in human embryonic stem cells
- Extracellular vesicle-mediated cross-talk during human brain development and disease
- From iPSC-Macrophage Biology Towards Regenerative Therapies Targeting Respiratory Infections
- Generation of position specific organoids to study human neuromuscular system development and disease
- Individualized Early Risk Assessment for Heart Diseases
- Inducible Human Photoreceptors for Research, Development and Therapy to Prevent Blindness
- Inducing functionality in retinal organoids with electrical activities derived from developing retina
- Maternally Inherited Leigh Syndrome
- Mechanisms of Presynaptic Biogenesis and Dynamic Remodeling
- Mediation of stem cell identity and aging by proteostasis
- Metabolic basis of neurodegenerative disease
- Metastable Epiallele: Role of Epigenetic Variability for the Development of Metabolic and Endocrine Diseases
- NAD+ Training
- Novel mechanisms of neurogenesis - from centrosome to engineering migration
- Parkinson's disease: does it all start with gut inflammation?
- Photomechanical writing of cell functions
- Retina Organoid Mechanobiology
- Safeguarding Cell Fate by Terminal Repression during Development and Disease
- Transcriptional Adaptation and Genetic Compensation
- Unraveling the mystery of preferential degeneration of midbrain neurons in neurodegenerative diseases
Provider
- (WITHDRAWN) Leipzig University
- (WITHDRAWN) University of TEST
- Axiogenesis AG
- Berlin Institute of Health
- BioCat GmbH
- BioMedX Innovation Center
- Catalent Düsseldorf
- Center for Child and Adolescent Medicine Heidelberg
- Center for Child and Adolescent Medicine Heidelberg - Dietmar Hopp Metabolic Center
- Center for Regenerative Therapies Dresden
- Center for Regenerative Therapies Dresden - Center for Molecular and Cellular Bioengineering
- Central Institute of Mental Health
- Central Institute of Mental Health - Department of Translational Brain Research
- Charité - Universitätsmedizin Berlin
- Charité - Universitätsmedizin Berlin - Berlin-Brandenburg Center for Regenerative Therapies
- Comprehensive Heart Failure Center, University Clinic Wuerzburg
- Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tuebingen
- Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tuebingen - Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tuebingen
- Department of Psychiatry, Psychotherapy and Psychosomatic Medicine, University Hospital, Goethe University of Frankfurt/Main
- Department of stem cell biology
- Department of Stem Cell Biology Universitätsklinikum Erlangen
- Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)
- Division of Paediatric Endocrinology and Diabetes
- Division of Paediatric Endocrinology and Diabetes - Department of Pediatrics, Medical Faculty, TU Dresden
- DZNE Munich
- EBiSC
- Fraunhofer Institute for Biomedical Engineering IBMT
- Fraunhofer Institute for Biomedical Engineering IBMT - Fraunhofer Institute for Biomedical Engineering IBMT
- Friedrich-Alexander Universität Erlangen-Nürnberg
- German Cancer Research Center
- German Center for Neurodegenerative Diseases
- German Heart Center Munich
- German Heart Center Munich, Department of Cardiovascular Surgery, Institute Insure
- Goethe University Frankfurt, IBC2, Münch lab
- Gottfried Wilhelm Leibniz Universitaet Hannover
- Hannover Medical School
- Heart and Diabetes Center North Rhine Westphalia
- Heidelberg University
- Heimer Institute for Muscle Research
- Heinrich-Heine-Universität Düsseldorf
- Heinrich-Heine-Universität Düsseldorf - Department of Molecular Cardiology, Düsseldorf
- Heinrich-Heine-Universität Düsseldorf - Institute for Stem Cell Research and Regenerative Medicine
- Heinrich-Heine-Universität Düsseldorf - Universitätsklinikum Düsseldorf
- Helmholtz Zentrum München
- Helmholtz Zentrum München - Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Centre Munich at the University of Tübingen
- Helmholtz Zentrum München - Institute for Stem Cell Research
- Helmholtz Zentrum München - Institute of Diabetes and Regeneration Research
- Hertie Institute for Clinical Brain Research - Clinical Neurogenetics
- Hertie Institute for Clinical Brain Research, AG Schüle
- Institut für Virologie und Zellbiologie
- Institute of Anatomy (University of Würzburg)
- Institute of Human Genetics Heidelberg
- Institute of Neurogenetics
- IUF – Leibniz Research Institute for Environmental Medicine
- Klinikum der Universität zu Köln
- Klinikum der Universität zu Köln - Centre for Physiology and Pathophysiology, Institute for Neurophysiology
- Klinikum der Universität zu Köln - Institute for Neurophysiology, Medical Faculty
- Leibniz Forschungslaboratorien für Biotechnologie und künstliche Organe
- Leibniz Institute for Environmental Medical Research GmbH
- Leibniz Institute for Environmental Medical Research GmbH
- Leibniz-Forschungsinstitut fuer Molekulare Pharmakologie im Forschungsverbund Berlin e.V.
- Leipzig University
- Leipzig University - Leipzig University Center for Biotechnology and Biomedicine
- Life & Brain GmbH
- Ludwig-Maximilians-Universität München
- Ludwig-Maximilians-Universität München - Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich
- Max Delbrück Center Berlin Buch
- Max Delbrück Center Berlin Buch - Transgenics (AG Kühn)
- Max Planck Institute for Heart and Lung Research
- Max Planck Institute for Molecular Biomedicine
- Max Planck Institute for Molecular Cell Biology and Genetics
- Max Planck Institute of Biochemistry
- Max Planck Institute of Psychiatry
- Medical Faculty of the Martin Luther University Halle-Wittenberg
- Miltenyi Biotec B.V. & Co. KG
- Neurologische Klinik
- NMI Natural and Medical Sciences Institute at the University of Tübingen
- None
- Paul-Ehrlich-Institut
- Reconstructive Neurobiology
- Technische Universität München
- Technische Universität München - Klinikum rechts der Isar
- TissUse GmbH
- Universität Duisburg-Essen
- Universitätsklinikum Aachen
- Universitätsklinikum Bonn
- Universitätsklinikum Erlangen
- Universitätsklinikum Essen
- Universitätsklinikum Würzburg
- Universitätsklinikum Würzburg - Division of Molecular Psychiatry, Center of Mental Health
- Universitätsklinikum Bonn
- Universitätsklinikum Bonn - Institut für Rekonstruktive Neurobiologie
- University Hospital Muenster
- University Medical Center Freiburg
- University Medical Center Goettingen
- University Medical Center Goettingen - Institute of Pharmacology & Toxicology
- University Medical Center Goettingen - Stem Cell Unit
- University Medical Center Hamburg-Eppendorf
- University Medicine Greifswald
- University Medicine Greifswald - Department of Functional Genomics - Human Molecular Genetics
- University Medicine Greifswald - University Medicine Greifswald - Department of Human Genetics
- University Medicine Rostock
- University Medicine Rostock - Translational Neurodegeneration Section "Albrecht Kossel"
- University of Freiburg
- University of Freiburg - Institute of Microsystem Engineering
- University of Tübingen, Hertie Institute for Clinical Brain Research, Group Fitzgerald
- Zentrum für Integrative Psychiatrie-ZiP gGmbH, Stem Cell Lab
hESC Cell lines
hiPSC Cell lines
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